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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1983 1
1984 3
1985 2
1986 2
1987 4
1988 3
1989 5
1990 6
1991 4
1992 5
1993 6
1994 5
1995 5
1996 3
1997 2
1998 2
1999 1
2001 1
2002 2
2003 2
2004 3
2005 3
2006 1
2007 1
2008 3
2009 1
2010 3
2011 6
2012 6
2013 2
2014 1
2015 4
2016 7
2017 8
2018 4
2019 5
2020 4
2021 6
2022 5
2023 3
2024 3

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130 results

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Page 1
A single-cell transcriptional atlas reveals resident progenitor cell niche functions in TMJ disc development and injury.
Bi R, Yin Q, Li H, Yang X, Wang Y, Li Q, Fang H, Li P, Lyu P, Fan Y, Ying B, Zhu S. Bi R, et al. Nat Commun. 2023 Feb 14;14(1):830. doi: 10.1038/s41467-023-36406-2. Nat Commun. 2023. PMID: 36788226 Free PMC article.
The lack of a detailed characterization of the network severely limits the development of targeted therapies for temporomandibular joint-related diseases. Here we profiled single-cell transcriptomes of disc cells from mice at different postnatal stages, finding that the fi …
The lack of a detailed characterization of the network severely limits the development of targeted therapies for temporomandibular joint-rel …
Reprogramming of cancer-associated fibroblasts by apoptotic cancer cells inhibits lung metastasis via Notch1-WISP-1 signaling.
Kim HJ, Yang K, Kim K, Lee YJ, Lee S, Ahn SY, Ahn YH, Kang JL. Kim HJ, et al. Cell Mol Immunol. 2022 Dec;19(12):1373-1391. doi: 10.1038/s41423-022-00930-w. Epub 2022 Oct 14. Cell Mol Immunol. 2022. PMID: 36241874 Free PMC article.
In addition, a single injection of ApoSQ enhanced WISP-1 production, suppressed the expression of CAF activation markers in isolated Thy1(+) CAFs, and inhibited lung metastasis in syngeneic immunocompetent mice via Notch1 signaling. ...Therefore, treatment with CM f …
In addition, a single injection of ApoSQ enhanced WISP-1 production, suppressed the expression of CAF activation markers in isolated Thy1 …
Mesenchymal-Epithelial Transition in Fibroblasts of Human Normal Lungs and Interstitial Lung Diseases.
Becerril C, Montaño M, Cisneros J, Mendoza-Milla C, Pardo A, Ortiz-Quintero B, Selman M, Ramos C. Becerril C, et al. Biomolecules. 2021 Mar 4;11(3):378. doi: 10.3390/biom11030378. Biomolecules. 2021. PMID: 33806618 Free PMC article.
In passages above ten and growing very actively, we observed that some human lung fibroblasts cultured under standard conditions were transformed into a lineage of epithelial-like cells (ELC). ...These findings suggest that the MET-like process can occur in human lung …
In passages above ten and growing very actively, we observed that some human lung fibroblasts cultured under standard conditions were …
Thy1 (+) and (-) lung fibrosis subpopulations in LEW and F344 rats.
McIntosh JC, Hagood JS, Richardson TL, Simecka JW. McIntosh JC, et al. Eur Respir J. 1994 Dec;7(12):2131-8. doi: 10.1183/09031936.94.07122131. Eur Respir J. 1994. PMID: 7536165 Free article.
Appreciation of the potential of fibroblasts as effector cells in inflammation has led to the recognition of fibroblast subpopulations, the most stable of which are the Thy1 (+) and Thy1 (-) subpopulations in mouse lung fibroblasts. We investigated the presen …
Appreciation of the potential of fibroblasts as effector cells in inflammation has led to the recognition of fibroblast subpopulations, the …
Up-regulation of THY1 attenuates interstitial pulmonary fibrosis and promotes lung fibroblast apoptosis during acute interstitial pneumonia by blockade of the WNT signaling pathway.
Chen L, Tang RZ, Ruan J, Zhu XB, Yang Y. Chen L, et al. Cell Cycle. 2019 Mar-Apr;18(6-7):670-681. doi: 10.1080/15384101.2019.1578144. Epub 2019 Mar 4. Cell Cycle. 2019. PMID: 30829553 Free PMC article.
Lung fibroblasts of mice were isolated, in which THY1 expression was altered to identify roles THY1 plays in cell viability and apoptosis. ...Cell proliferation was inhibited and apoptosis was accelerated in lung fibroblasts transfected with vector car …
Lung fibroblasts of mice were isolated, in which THY1 expression was altered to identify roles THY1 plays in cell viabi …
Transcriptome-level discovery of survival-associated biomarkers and therapy targets in non-small-cell lung cancer.
Győrffy B. Győrffy B. Br J Pharmacol. 2024 Feb;181(3):362-374. doi: 10.1111/bph.16257. Epub 2023 Nov 23. Br J Pharmacol. 2024. PMID: 37783508
BACKGROUND AND PURPOSE: Survival rate of patients with lung cancer has increased by over 60% in the recent two decades. ...We also aimed to reveal the best druggable targets in non-smokers lung cancer. The three most promising hits in this cohort were MDK, THY1 …
BACKGROUND AND PURPOSE: Survival rate of patients with lung cancer has increased by over 60% in the recent two decades. ...We also ai …
Thy1 is a positive regulator of osteoblast differentiation and modulates bone homeostasis in obese mice.
Paine A, Woeller CF, Zhang H, de la Luz Garcia-Hernandez M, Huertas N, Xing L, Phipps RP, Ritchlin CT. Paine A, et al. FASEB J. 2018 Jun;32(6):3174-3183. doi: 10.1096/fj.201701379R. Epub 2018 Jan 17. FASEB J. 2018. PMID: 29401595 Free PMC article.
The role of Thy1 on bone structure and function has been poorly studied and represents a major knowledge gap. ...Consistent with micro-CT measurements, histomorphometric analysis also showed decreased bone volume in the obese Thy1 KO mice compared to obese WT mice. …
The role of Thy1 on bone structure and function has been poorly studied and represents a major knowledge gap. ...Consistent with micr …
Bleomycin-Treated Chimeric Thy1-Deficient Mice with Thy1-Deficient Myofibroblasts and Thy-Positive Lymphocytes Resolve Inflammation without Affecting the Fibrotic Response.
Cohen PY, Breuer R, Zisman P, Wallach-Dayan SB. Cohen PY, et al. Mediators Inflamm. 2015;2015:942179. doi: 10.1155/2015/942179. Epub 2015 Aug 2. Mediators Inflamm. 2015. PMID: 26300593 Free PMC article.
We aimed to identify genetic changes in lung myofibroblasts following Thy1 crosslinking and assess the impact of specific lung myofibroblast Thy1-deficiency, in vivo, in bleomycin-injured mouse lungs. ...Lung myofibroblasts downregulate Thy1 …
We aimed to identify genetic changes in lung myofibroblasts following Thy1 crosslinking and assess the impact of specific l …
Differential Expression Pattern of THBS1 and THBS2 in Lung Cancer: Clinical Outcome and a Systematic-Analysis of Microarray Databases.
Weng TY, Wang CY, Hung YH, Chen WC, Chen YL, Lai MD. Weng TY, et al. PLoS One. 2016 Aug 11;11(8):e0161007. doi: 10.1371/journal.pone.0161007. eCollection 2016. PLoS One. 2016. PMID: 27513329 Free PMC article.
THBS1 was in general underexpressed in lung cancer; in contrast, mRNA levels of THBS2 were markedly overexpressed in a number of datasets of non-small cell lung carcinoma (NSCLC), including lung adenocarcinoma (AC) and squamous cell carcinoma. ...In summary, …
THBS1 was in general underexpressed in lung cancer; in contrast, mRNA levels of THBS2 were markedly overexpressed in a number of data …
Different effects of titanium dioxide nanoparticles instillation in young and adult mice on DNA methylation related with lung inflammation and fibrosis.
Ma Y, Guo Y, Ye H, Huang K, Lv Z, Ke Y. Ma Y, et al. Ecotoxicol Environ Saf. 2019 Jul 30;176:1-10. doi: 10.1016/j.ecoenv.2019.03.055. Epub 2019 Mar 21. Ecotoxicol Environ Saf. 2019. PMID: 30903973
Epigenetic mechanisms, such as DNA methylation, have been found to play a role in the development of lung diseases by affecting expression of key genes. In addition, there could be potential different toxic effects of TiO(2) NPs between young and adult. Thus, the co …
Epigenetic mechanisms, such as DNA methylation, have been found to play a role in the development of lung diseases by affectin …
130 results